L-Tyrosine is a non-essential amino acid which acts as a precursor to dopamine and noradrenaline. [1]

It can exert notable acute cognitive benefits when the situation demands for an increased availability of dopamine and noradrenaline.

For example, during sleep deprivation, L-Tyrosine can positively enhance cognitive functions, such as running memory, logical reasoning, visual vigilance and mathematical processing. [2]

Under stressful conditions, L-Tyrosine can improve short-term memory, processing speed, selective attention, automaticity and perceptual-motor skills. [3][4]

The aforementioned benefits have been observed in clinical trials, with L-Tyrosine dosages ranging from 2-12 grams. Our dosage of 700 milligrams aims to be a supporting dose next to the natural synthesis of L-Tyrosine from phenylalanine and, should it be needed, alleviate the detriments of depleted dopamine and noradrenaline levels.


Citicoline, also known as cytidine diphosphate-choline is a naturally occuring molecule in humans. When taken as a supplement, citicoline is metabolized to choline and cytidine. [5]

The biosynthetic pathway of citicoline provides sources of precursors for the synthesis of the neurotransmitter acetylcholine and cell membranes. [6]

Clinical trials have found that citicoline supplementation improves attention, focus and learning in large part due to the increase in acetylcholine that results. [7]

Studies also suggest that increasing the amount of essential structural components of cell membranes, may mitigate cognitive declines associated with aging. [6]

We have included citicoline in ENLIGHTENMENT 2.0 at the maximum daily dose of 500 mg.

Bacopa monnieri Extract

Bacopa monnieri is a perennial herb, that has been used in Ayurvedic medicine for thousands of years. [8]

A number of controlled studies utilizing standardized Bacopa monnieri extracts have described its cognitive enhancing effects upon human cognition.

Bacopa monnieri can acutely improve cognition in areas, such as reasoning and cognitive speed. [9]

Supplementing Bacopa monnieri over a longer period of time, can improve verbal learning, memory acquisition and attention. [10][11]

Bacopa monnieri may also have neuroprotective effects as well. Standardized Bacopa monnieri extracts have been shown to scavenge reactive oxygen species, reduce beta-amyloid levels in the brain and also increase dendritic length and branching points. [12][13]

We have included Bacopa monnieri in our formula as an extract standardized to 50% bacosides at 350 mg.


Phosphatidylserine is a phospholipid and is a component of the cell membrane. [14]

Phosphatidylserine is required for healthy nerve cell membranes and myelin. In 2015 a scientific paper reviewing 127 research articles, was published. The researchers concluded, that exogenous phosphatidylserine (300-800 mg daily) is absorbed safely and efficiently in humans. [15]

Also, phosphatidylserine was found to support the formation of short-term memory, consolidation of long-term memory, the ability to communicate, reason, solve problems, concentrate and create new memories. [15]

ENLIGHTENMENT 2.0 has a 300 mg dose of 50% phosphatidylserine.


L-Theanine is an amino acid, that is primarily found in particular plants, like green tea, and fungal species.

In humans, L-Theanine has been found to exert anti-stress effects during acutely stressful situations. [16][17]

For cognitive functions, improvements in verbal fluency, problem-solving, reasoning and planning skills have been observed, when L-Theanine was taken daily for 4 weeks. [16]

Numerous studies have also investigated the syngerstic effect of combined L-Theanine and caffeine intake. These research papers have found improvements in many areas of cognition, such as reaction time, alertness, working memory and mental fatigue. [18]

All of these benefits of L-Theanine have been observed by scientists at dosages ranging from 36-400 milligrams per day and above.

ENLIGHTENMENT 2.0 has a 100 mg dose of L-Theanine, extracted and isolated from green tea.

Saffron Extract

Saffron is a spice obtained from the flower of Crocus sativus. In recent years, researchers have begun to look into the potential therapeutic effects of standardized Saffron extracts.

Multiple studies have been conducted to assess the effects of Saffron on mood and attention span in humans. Although great outcomes have been observed in patients diagnosed with ADHD or depression, improvements regarding mood, anxiety and attention have been found in healthy individuals as well.

In short, saffron extract has been shown to significantly decrease negative mood and symptoms related to stress and anxiety in healthy people. [19][20]

The main active constituents of Saffron are thought to be crocins and safranal. There is evidence that crocins act as reuptake inhibitors of dopamine and noradrenaline, while safranal acts primarily on serotonin reuptake. [21][22][23]

Researchers have observed the aforementioned benefits with dosages ranging from 15-30 milligrams.

We have included Saffron in ENLIGHTENMENT 2.0 as an extract, standardized to 0.3% safranals at a dose of 30 milligrams.


Say goodbye to proprietary blends and hello to transparent formulas.


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